Anticancer Induced Nephrotoxicity: A Review

Introduction: Drug-induced adverse effects are the major challenging issue in clinical setting of chemotherapy. Kidneys responsible for elimination many chemotherapeutic agents which makes them a common target effects. Nephrotoxicity is deleterious effect carrying great negative impact on body homeostasis and maintenance cellular functions.Aim: The present review aims to focus anticancer-induced nephrotoxicity including causes mechanisms toxicity.Methods: Different databases published materials recruited mainly from PubMed, Google Scholars, Iraqi Virtual Science Library.Results: shows that recurrent use anticancer drugs can cause different types kidney damage via mechanisms.Conclusion: Anticancer-induced crucial problem needs more research clarify methods prevent them. Maintaining appropriate enough hydration, electrolyte replacement, avoiding concomitant medications useful steps overcoming nephrotoxicity.